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Germ Cells
In the adult mouse testis, all germ cells are labeled with DAZL (green) while only the undifferentiated germ cells express YBX1 (red). All cell nuclei are labeled with DAPI (blue). Image from MGDB Alum Bart Phillips, from Dr. Orwig's lab.
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Dystrophin membrane staining
Immunostaining image of dystrophin membrane staining with the blue DAPI counterstain -- of a mouse tongue in cross-section. Image from the Clemens laboratory.
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Human mesenchymal stem cells
Human mesenchymal stem cells labeled with DiO (Green) co-cultured with human endothelial cells labeled with DiI (Pink) on Matrigel for 24 hours. The sample has been stained with DAPI (Blue) and immunostained for MCAM (Red). Image from Tom Lozito in Dr. Tuan's lab.
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Transgenic Zebrafish
Transgenic Zebrafish at 28 hours post fertilization showing fluorescent labeling of mid-hindbrain, trigeminal ganglia, retina and lens. Image from the lab of Dr. Michael Tsang.
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Drosophila embryo
Drosophila embryo with disrupted cell polarity (apical marker in green) due to overexpression of a hyperactive Receptor Tyrosine Kinase. Image from the lab of Dr. Beth Stronach.
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Zebrafish Heart Staining
Regenerating zebrafish heart stained with PCNA (Red) for proliferating cells and Mef2C (Green) for cardiomyocytes. Image from the lab of Dr. Michael Tsang.

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About MGDB
image Mesenchymal stem cells seeded on electrospun polycaprolactone nanofibers. Image from Allison Bean in Dr. Tuan's laboratory.

The Molecular Genetics and Developmental Biology (MGDB) graduate program provides an exceptionally exciting and vigorous academic environment for highly motivated and qualified students to prepare for a rewarding career in biomedical research.  The members of the faculty have a wide diversity of interests and are pursuing research projects that address fundamental, contemporary issues in biology and medicine.  We are also committed to postgraduate education and share as a major objective the integration of students into the most important aspects of our investigative work. 

MGDB research is at the cutting edge of many emerging fields, including developmental and reproductive biology, stem cell biology, proteomics, computational biology and geonomics. Our work has direct relevance to acute injury, congenital disorders, cancer, diabetes, muscular dystrophy...