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Saman Eghtesad, PhD Postdoctoral Fellow



Dr. Saman Eghtesad

Contact

Mentor

Dr. Paula Clemens

Education

PhD in Molecular Genetics and Developmental Biology, University of Pittsburgh, School of Medicine, 2010

BS in Biology, Univeristy of New Mexico


Why I chose Pitt

Good academic environment with a direct Ph.D. program; Immediate family living in Pittsburgh; Nice city.

After her graduation from Pitt, Saman accepted a position as a Post-doctoral fellow at the University of Maryland School of Medicine, Department of Surgery, Division of Surgical Research.

Abstracts 

Eghtesad S., Howard T.A., Reinert B.L., Fleet T.M., Jett S.D., Bear D.G. "Temporal Titin Expression in Mouse Skeletal Muscle." University of New Mexico 11th Annual Science Day (2002)

Eghtesad S., Zheng H., Jhunjhunwala S., Little S., Clemens P.R. "Induction of Tolerance to High-Capacity Adenoviral Vector-Mediated Full-Length Dystrophin cDNA Transfer in Duchenne Muscular Dystrophy Mouse Model, mdx." Ohio State University and Nationwide Children’s Muscle Symposium (2009)

Eghtesad S., Zheng H., Nakai H., Epperly M.W., Clemens P.R. "Irradiation of adult mdx mice prior to full-length murine dystrophin cDNA transfer results in a delayed and diminished anti-dystrophin host immune response." American Society of Gene and Cell Therapy 13th Annual Meeting (2010)

Eghtesad S., Nurminskaya, M.V. “Vascular smooth muscle cell migration toward mesenchymal stem cell-seeded PLLA scaffold.” Biochemistry and Molecular Biology Muscle Mini Retreat; Baltimore, MD (2012)

Beazley K., Eghtesad, S., Nurminskaya M. “Quercetin attenuates warfarin-induced vascular calcification in vitro.” American Society of Matrix Biology; San Diego, CA (2012)

Eghtesad S., Nurminskaya, M. “Vascular smooth muscle cell migration toward mesenchymal stem cell-seeded and unseeded PLLA scaffolds for vascular bioengineering.” Cardiovascular and Muscle Retreat; Baltimore, MD (2012)

Publications

Effect of rapamycin on immunity induced by vector-mediated dystrophin expression in mdx skeletal muscle. Sci Rep. 2: 399. |  View Abstract

Quercetin attenuates warfarin-induced vascular calcification in vitro independently from Matrix Gla protein. J Biol Chem. [Epub ahead of print]. |  View Abstract

Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle. Mol Med. 17: 917-924. |  View Abstract

Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity. Gene Ther. 17: 1181-1190. |  View Abstract

The companions: regulatory T cells and gene therapy. Immunology. 127: 1-7. |  View Abstract

Gene therapy for muscular dystrophy reaches human clinical trial. Ann Neurol. 66: 267-270. |  View Abstract