Contact
Mentor
Dr. Paula Clemens
Education
PhD in Molecular Genetics and Developmental Biology, University of Pittsburgh, School of Medicine, 2010
BS in Biology, Univeristy of New Mexico
Why I chose Pitt
Good academic environment with a direct Ph.D. program; Immediate family living in Pittsburgh; Nice city.
After her graduation from Pitt, Saman accepted a position as a Post-doctoral fellow at the University of Maryland School of Medicine, Department of Surgery, Division of Surgical Research.
Abstracts
Eghtesad S., Howard T.A., Reinert B.L., Fleet T.M., Jett S.D., Bear D.G. "Temporal Titin Expression in Mouse Skeletal Muscle." University of New Mexico 11th Annual Science Day (2002)
Eghtesad S., Zheng H., Jhunjhunwala S., Little S., Clemens P.R. "Induction of Tolerance to High-Capacity Adenoviral Vector-Mediated Full-Length Dystrophin cDNA Transfer in Duchenne Muscular Dystrophy Mouse Model, mdx." Ohio State University and Nationwide Children’s Muscle Symposium (2009)
Eghtesad S., Zheng H., Nakai H., Epperly M.W., Clemens P.R. "Irradiation of adult mdx mice prior to full-length murine dystrophin cDNA transfer results in a delayed and diminished anti-dystrophin host immune response." American Society of Gene and Cell Therapy 13th Annual Meeting (2010)
Eghtesad S., Nurminskaya, M.V. “Vascular smooth muscle cell migration toward mesenchymal stem cell-seeded PLLA scaffold.” Biochemistry and Molecular Biology Muscle Mini Retreat; Baltimore, MD (2012)
Beazley K., Eghtesad, S., Nurminskaya M. “Quercetin attenuates warfarin-induced vascular calcification in vitro.” American Society of Matrix Biology; San Diego, CA (2012)
Eghtesad S., Nurminskaya, M. “Vascular smooth muscle cell migration toward mesenchymal stem cell-seeded and unseeded PLLA scaffolds for vascular bioengineering.” Cardiovascular and Muscle Retreat; Baltimore, MD (2012)
Publications
Effect of rapamycin on immunity induced by vector-mediated dystrophin expression in mdx skeletal muscle. Sci Rep. 2: 399. | View Abstract
Quercetin attenuates warfarin-induced vascular calcification in vitro independently from Matrix Gla protein. J Biol Chem. [Epub ahead of print]. | View Abstract
Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle. Mol Med. 17: 917-924. | View Abstract
Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity. Gene Ther. 17: 1181-1190. | View Abstract
The companions: regulatory T cells and gene therapy. Immunology. 127: 1-7. | View Abstract
Gene therapy for muscular dystrophy reaches human clinical trial. Ann Neurol. 66: 267-270. | View Abstract